Coronary Artery Disease
Development of Coronary Artery Disease (CAD)
Coronary artery disease represents an obstruction or constricting (stenosis) of vessels and arteries which supplies the heart with oxygenated blood. The cause for CAD is atherosclerosis (arterial hardening), or a fatty plaque buildup on inner arterial linings. The resultant obstruction impedes blood flow across coronary arteries. The complete cut- off of blood flow leads to a heart attack (or myocardial infarction, in medical terms). CAD takes place when coronary arteries are partly obstructed or hindered, thus cutting off oxygen supply to heart muscles (i.e., myocardial ischemia). When the blockage is temporary or partial, angina (chest pain or pressure) may occur. The sudden, complete cut- off of blood flow due to the blockage leads to myocardial infarction (Milto, Costello, Davidson & Lerner, 2013).
CAD is a condition that sets it from a rather young age, a fact not many are aware of. Prior to adolescence, the walls of blood vessels start showing fat streaks. With age, this fat accumulates, injuring blood vessel walls to some extent. Proteins, calcium, inflammatory cells, cellular wastes and other substances which traverse an individual’s blood stream start sticking to vessel walls. These substances (including fat) join up with each other and form another substance – plaque. With time, the arterial interior develops plaques of varying sizes, several of which tend to be soft (internally), with a tough fibrous external "cap". The...
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